Project Manager, Translational Research

Mississauga, Ontario


Trillium Therapeutics is a clinical stage immuno-oncology company based in Cambridge, MA and Toronto, ON. Following recent promising clinical data updates and after raising over $300 million in 2020, the Company has embarked on a substantial organizational scale-up and initiated an ambitious phase 1b/2 program across a range of cancer indications. The Company is seeking a Project Manager, Translational Research, who will report to the Director, Translational Research. The Project Manager will provide overall support and coordination of translational research projects, working closely with cross-functional teams to ensure successful implementation and execution of projects.

This position will be based in Mississauga, ON.

The Company

Trillium Therapeutics (Nasdaq:TRIL) is a clinical stage biotechnology company developing next generation immunotherapies targeting CD47, a checkpoint of the innate immune system. Immunotherapy is a rapidly evolving field that is redefining cancer care by harnessing a patient’s own immune system to eliminate tumor cells. First generation immunotherapies, targeting the adaptive immune system via T cell checkpoint inhibitors, have been enormously successful scientifically (2018 Nobel prize), clinically (achieving real cure rates), and commercially (soon to be the largest drug class ever). CD47 is now emerging as one of the most promising next generation immuno-oncology targets.

Trillium has two highly differentiated CD47 blockers in development that – unlike other CD47 agents – have shown unique monotherapy activity across a range of hematologic malignancies. Under new leadership, Trillium has undergone a wide-ranging transformation program, including a major strategy reset. In 2020, the company raised over $300M and secured a strategic investment from Pfizer. After initiating an ambitious Phase 1b/2 program across multiple hematologic and solid tumor indications earlier this year, Trillium is now scaling up its organization to ensure strong execution of the program.

The Position

The Project Manager, Translational Research is responsible for coordinating and managing resources of various translational research activities. These activities include but are not limited to preclinical study management, CRO, translational research vendor management, managing and receiving data and study reports, and supporting review of clinical trial related documents.


  • Manage and provide support to translational research projects, including but not limited to outsourced biomarker sample analysis and pre-clinical animal studies. Coordinate with CRO, manage project activities from start up to close out.
  • Vendor management and vendor oversight– including but not limited to CROs, academic institutions, translational vendors:
    • Manage contracts, statement of work, request for proposal (RFP) and affiliated vendor start up activities.
    • Proactively track and manage project tasks against timelines.
    • Ensure deliverables, timelines, and milestones for contracted services are on track.
    • Work closely and manage relationships with external vendors and the internal team.
    • Manage correspondence, updates and follow up with vendors to ensure efficient project progression and issue resolution as appropriate.
    • Prepare project status reports and maintain accurate and current details.
  • Work closely with cross-functional teams in the development, management and execution of project plans.
  • Provide support in the review and/or co-ordination of review of internal and/or external study documents including study protocols, reports, and other translational research and clinical study related documents.
  • Contribute to review and QC of translational research data prior to public disclosure and support preparation of internal data summaries.
  • Work closely with, and manage consultants as required to support successful project execution.
  • Assist in tracking of clinical samples. Coordinate and facilitate clinical sample shipment by working with clinical operation team, translational research team, CROs and FedEx.
  • Coordinate with external parties for maintenance of the lab and lab equipment. Ensure that critical equipment is maintained and serviced up-to-date.
  • Provide support as required to the Director, Translational Research.
  • Other duties as required.
  • Work in compliance with the Trillium’s Code of Business Conduct and Ethics and all workplace policies, procedures and regulations.


  • Bachelor of Science; Master of Science preferred.
  • Minimum of 5 years of experience in pharmaceutical or biotech drug development setting.
  • Project Management experience.
  • Demonstrated experience in dealing with a wide variety of project stakeholders at all levels.
  • Strong communication and interpersonal skills.
  • Highly proficient in MS Office Suite (Word, Excel, PowerPoint, MS Project, MS Access).
  • Extended work day or week-end work and flexible working hours may be required.
  • Some travel may be required.

Personal Attributes

  • Strong values-driven individual able to function in a diverse, cross-functional and multi-disciplinary team.
  • Must be willing and able to be “hands-on”, and thrive in a matrixed, fast-paced, dynamic and changing business environment.
  • Exceptional interpersonal skills and willingness to collaborate with others on assigned projects (including both internal teams and external parties).
  • Keen attention to detail and demonstrated ability to multitask.
  • Critical thinker with demonstrated ability to proactively identify issues and mitigate risks.
  • Highly versatile with ability to swiftly shift focus while attending to multiple competing priorities.
  • Exceptional organizational skills.

The duties and responsibilities contained in the job description are not exhaustive and may be changed by the Company at any time.

How to Apply

Please send your resume and cover letter to with the title of the role in the subject line. Kindly note that phone calls and third parties are not accepted.

We thank all applicants for their interest. We will be reaching out only to candidates whose backgrounds most closely match our needs.