About Us

Trillium Therapeutics is an immuno-oncology company developing innovative therapies for the treatment of cancer. The Company’s two clinical programs, TTI-621 and TTI-622, target CD47, a “don’t eat me” signal that cancer cells frequently use to evade the immune system.

Formed in Ontario and named after the province’s official flower, Trillium grandiflorum, Trillium Therapeutics is an immuno-oncology company targeting CD47, a molecule that tumors frequently use to evade the immune system. CD47 is a “don’t eat me” signal that blocks the ability of macrophages to phagocytose and destroy tumor cells. By blocking this “don’t eat me” signal with decoy receptors, we aim to unmask tumor cells and make them visible to the immune system. As a leading CD47-focused company, Trillium Therapeutics has two decoy receptors (TTI-621 and TTI-622) that are currently being evaluated in patients with hematological malignancies.

At the end of 2019, under new leadership, Trillium underwent a transformational program that included corporate reorganization, the creation of a more clinical development-centric organization and strategic re-prioritization to focus on our intravenous products in large hematology-oncology indications. With offices in Cambridge, MA, USA and Mississauga, ON, Canada, Trillium is home to a globally diverse group of people dedicated to improving the lives of cancer patients.

Management Team

Board of Directors

Scientific Advisory Board